Paper 13308-12
Paper 13308-12
Fabrication of tissue-mimicking epidermis phantom layers with tunable pigmentation
25 January 2025 • 2:25 PM - 2:45 PM PST
Abstract
Clinical studies have indicated that epidermal pigmentation can significantly impact the accuracy of pulse oximetry. Towards a phantom-based test method for pulse oximetry, we present a modified and streamlined method for fabricating 0.1-mm-thick epidermal layer phantoms based on readily available chemical components. We were able to achieve optical property values within 10% of target levels across the 660 nm to 940 nm range for low, medium and high pigmentation cases. This technique provides reproducible and stable epidermal phantoms suitable for evaluating the impact of pigmentation on oximeters and other biophotonic devices.
Presenter
Md Sadique Hasan
U.S. Food and Drug Administration (United States)
Dr. Md Sadique Hasan received his PhD in Electrical Engineering from the University of Maryland Baltimore County (UMBC) in 2023. Following his graduation, he joined the FDA as a postdoctoral ORISE fellow. Dr. Hasan's expertise lies in preparing phantoms to test and validate various optical devices and in fostering research collaborations. His research focuses on creating test methods through the fabrication of phantoms to assess the performance and accuracy of optical devices, particularly oximeters. His work is dedicated to advancing diagnostic technologies and ensuring their effectiveness, reliability, and precision.