Paper 13111-34
Paper 13111-34
Plasmonic metasurfaces for biosensing and imaging (Invited Paper)
20 August 2024 • 2:35 PM - 3:00 PM PDT | Conv. Ctr. Room 4
Abstract
Mid-infrared (MIR) vibrational spectroscopy is a non-invasive and label-free analytical method; thus, it has become an essential technique for examining biological samples and tissues. Research has shown that this method, MIR spectral imaging (MIRSI), can identify various diseases with implications for enhanced biomedical tissue diagnostics. Nonetheless, the diverse chemical makeup of tissues and their spatial heterogeneity, combined with the innately weak interaction between infrared light and biological molecules, limit the efficacy of conventional MIRSI. We introduce a new chemical tissue analysis method that uses plasmonic metasurfaces enabling the detailed molecular mapping of tissue sections. The proposed surface-enhanced chemical imaging method using plasmonic metasurfaces has excellent potential for translational biomedical research and clinical histopathology.
Presenter
Univ. of Wisconsin-Madison (United States)
Dr. Filiz Yesilkoy is an assistant professor in the Biomedical Engineering Department at the UW–Madison. With a focus on integrating engineering tools with biomedical applications, Dr. Yesilkoy’s research specializes in developing novel nanophotonic devices, aiming to pioneer next-generation label-free biosensors and spectrochemical tissue imaging methods. These advancements hold significant potential for improving the accuracy and effectiveness of medical diagnostics. In 2012, Dr. Yesilkoy earned her Ph.D. in Electrical Engineering from the University of Maryland, College Park, supported by the Fulbright Scholarship. Then, she engaged in impactful post-doctoral research at the Swiss Federal Institute of Technology Lausanne and the University of Tokyo in Japan. Dr. Yesilkoy has cultivated a robust research portfolio, including over 20 peer-reviewed publications. In 2023, her contributions to the field were recognized with the Trailblazer Award from the NIBIB at the NIH.