Program now available
Registration open
>
16 - 20 February 2025
San Diego, California, US
Conference 13405 > Paper 13405-60
Paper 13405-60

Deep learning reconstruction of triple-source CT data with sparse view and truncation

17 February 2025 • 5:30 PM - 7:00 PM PST | Golden State Ballroom

Abstract

Cardiovascular disease remains a leading cause of global mortality, driving innovation in cardiac imaging. Interior tomography, which limits x-ray beams to a specific region of interest (ROI), significantly reduces radiation exposure, making it ideal for cardiac applications. A Triple-Source CT (TSCT) capable of performing interior tomography of the heart using three simultaneous imaging chains shows promise for rapid, low-dose cardiac imaging. However, conventional analytic reconstruction algorithms struggle with severe artifacts due to data truncation and sparse-view sampling. In this paper, we propose a novel interpolation-based dual-task network for deep reconstruction of cardiac CT images in TSCT. Our approach employs two sub-networks that address sparse-view and truncation artifacts separately, leveraging distinct ground truths to constrain each sub-network during training. This separation simplifies training and enables more focused and effective artifact removal. Additionally, we utilize two interpolation methods to complete the sinogram as a prior input, enhancing reconstruction accuracy. Experimental results from imaging a porcine heart using 84 views and a 31.3% truncation ratio demonstrate that our method effectively suppresses both artifact types while preserving image details. Compared to conventional FBP, our approach achieves improvements of 40% in RMSE and 6% in SSIM. This reconstruction method shows potential for cardiac imaging in TSCT systems.

Presenter

ShanghaiTech Univ. (China)
Guohua Cao is an Associate Professor and heads the X-ray Systems Lab at ShanghaiTech University's School of Biomedical Engineering in China. He earned his PhD from Brown University in the United States after completing his undergraduate studies at the University of Science and Technology of China. Prior to joining ShanghaiTech in 2021, he held positions as an Assistant Professor of Physics at the University of North Carolina at Chapel Hill, as well as an Assistant Professor of Biomedical Engineering and Computer Science at Virginia Tech. Dr. Cao's research is centered around biomedical imaging, focusing on developing innovative imaging tools. His team achieved a major breakthrough by creating a carbon nanotube micro-CT that can capture detailed images of a beating mouse heart. He also pioneered a stationary CT architecture that holds potential for stop-action cardiac CT examinations. He has published more than 100 research papers in respected journals.
Application tracks: AI/ML
Author
Ying Cheng
ShanghaiTech Univ. (China)
Author
Zhe Wang
ShanghaiTech Univ. (China)
Author
Linjie Chen
ShanghaiTech Univ. (China)
Author
ShanghaiTech Univ. (China)
Presenter/Author
ShanghaiTech Univ. (China)