
Proceedings Paper
Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutionsFormat | Member Price | Non-Member Price |
---|---|---|
$17.00 | $21.00 |
Paper Abstract
Methods of femtosecond laser ablation in deionized water were used to fabricate ultrasmall (< 2 nm), bare (ligand-free) organic luminophore DCEtDCS nanoparticles, which exhibit aggregation enhanced emission in the green range (533 nm) with the quantum yield exceeding 58% and provide no concentration quenching. In contrast to chemically synthesized counterparts, laser-synthesized DCEtDCS nanoparticles do not contain any organic impurities due to their preparation in aqueous medium and do not require surfactants to stabilize colloidal solutions, which makes them highly suitable for intracellular uptake and bioimaging. The highly negative surface charge of these nanoparticles impeded their cellular uptake, but when the surface was coated with chitosan, a cationic polymer, intracellular uptake in microglia was achieved. Using in vitro model, we finally demonstrate the efficient employment of ultrasmall and surfactant free fluorescent organic nanoparticles prepared by laser ablation as markers in bioimaging.
Paper Details
Date Published: 4 March 2019
PDF
Proc. SPIE 10907, Synthesis and Photonics of Nanoscale Materials XVI, 109070U (4 March 2019); doi: 10.1117/12.2513821
Published in SPIE Proceedings Vol. 10907:
Synthesis and Photonics of Nanoscale Materials XVI
Andrei V. Kabashin; Jan J. Dubowski; David B. Geohegan, Editor(s)
Proc. SPIE 10907, Synthesis and Photonics of Nanoscale Materials XVI, 109070U (4 March 2019); doi: 10.1117/12.2513821
Show Author Affiliations
C.-K. Lim, Univ. at Buffalo (United States)
A. A. Popov, Aix-Marseille Univ., CNRS, LP3 (France)
G. Tselikov, Aix-Marseille Univ., CNRS, LP3 (France)
J. Heo, KAIST (Korea, Republic of)
A. A. Popov, Aix-Marseille Univ., CNRS, LP3 (France)
G. Tselikov, Aix-Marseille Univ., CNRS, LP3 (France)
J. Heo, KAIST (Korea, Republic of)
A. Pliss, Univ. at Buffalo (United States)
S. Kim, KAIST (Korea, Republic of)
A. V. Kabashin, Aix-Marseille Univ., CNRS, LP3 (France)
MEPhI, Bio-Nanophotonic Lab. (Russian Federation)
P. N. Prasad, Univ. at Buffalo (United States)
MEPhI, Bio-Nanophotonic Lab. (Russian Federation)
S. Kim, KAIST (Korea, Republic of)
A. V. Kabashin, Aix-Marseille Univ., CNRS, LP3 (France)
MEPhI, Bio-Nanophotonic Lab. (Russian Federation)
P. N. Prasad, Univ. at Buffalo (United States)
MEPhI, Bio-Nanophotonic Lab. (Russian Federation)
Published in SPIE Proceedings Vol. 10907:
Synthesis and Photonics of Nanoscale Materials XVI
Andrei V. Kabashin; Jan J. Dubowski; David B. Geohegan, Editor(s)
© SPIE. Terms of Use
