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Proceedings Paper

Measurements of light penetration into human tissues in vivo
Author(s): Vladimir Iani; Johan Moan; Li Wei Ma
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Paper Abstract

A main factor to consider before photochemotherapy (PCT) is chosen to treat a tumor is whether sufficient fluences of light can reach the base of the tumor. The choice of optimal wavelengths for PCT should also be based on a knowledge of the optical penetration spectrum of the tumor. By means of a fiberoptic probe, adapted to a commercial fluorescence spectrometer, it is possible to measure the penetration depths of visible light into living, human tissues. We have performed such experiments, using the light from a 1000 W Xenon lamp. The light was guided from the lamp to the tissue by a perspex rod and the fluence rate penetrating different thickness of tissue was monitored by the fiberoptic probe. From penetration curves obtained at a number of wavelengths, it was possible to construct an accurate optical penetration spectrum of the tissue.

Paper Details

Date Published: 31 January 1996
PDF: 6 pages
Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); doi: 10.1117/12.230985
Show Author Affiliations
Vladimir Iani, Institute for Cancer Research (Norway)
Johan Moan, Institute for Cancer Research (Norway)
Li Wei Ma, Institute for Cancer Research (Norway)

Published in SPIE Proceedings Vol. 2625:
Photochemotherapy: Photodynamic Therapy and Other Modalities
Benjamin Ehrenberg; Giulio Jori; Johan Moan, Editor(s)

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