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Proceedings Paper

Toxicological evaluation of Cd-based fluorescent nanoprobes by means of in vivo studies
Author(s): Patricia M. A. Farias; Lan Ma-Hock; Robert Landsiedel; Bennard van Ravenzwaay
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Paper Abstract

Cadmium still represents a stigma for many research- and/or industrial applications. Some deleterious effects are attributed to Cadmium. In the present work, highly fluorescent Cadmium sulfide quantum dots are investigated by e.g. physical-chemical characterization. Most important however is their application as fluorescent probes for bio-imaging in living cells and tissues. This work presents their toxicological evaluation by means of in vivo studies. Bio-imaging experiments are performed without any pre-treatment. The toxicological studies performed, strongly indicate that the use of Cadmium based nanoparticles as fluorescent probes may be nonhazardous and not induce side effects for cells/tissues.

Paper Details

Date Published: 20 February 2018
PDF: 5 pages
Proc. SPIE 10508, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications X, 105080H (20 February 2018); doi: 10.1117/12.2289341
Show Author Affiliations
Patricia M. A. Farias, Federal Univ. of Pernambuco (Brazil)
CETENE (Brazil)
Phornano GmbH (Austria)
Lan Ma-Hock, BASF SE (Germany)
Robert Landsiedel, BASF SE (Germany)
Bennard van Ravenzwaay, BASF SE (Germany)


Published in SPIE Proceedings Vol. 10508:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications X
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

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