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Proceedings Paper

Development of a cylindrical diffusing optical fiber probe for pancreatic cancer therapy
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Paper Abstract

Although the patients with cancer on pancreas or pancreaticobiliary duct have been increased, it is very difficult to detect and to treat the pancreatic cancer because of its low accessibility and obtuseness. The pancreatic cancer has been diagnosed using ultrasonography, blood test, CT, endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasonography (EUS) and etc. Normally, light can be delivered to the target by optical fibers through the ERCP or EUS. Diffusing optical fibers have been developed with various methods. However, many of them have mechanical and biological problems in the use of small-bend-radius apparatus or in tissue area. This study developed a therapeutic cylindrical diffusing optical fiber probe (CDOFP) for ERCP and EUS which has moderate flexibility and solidity to treat the cancer on pancreaticobiliary duct or pancreas. The CDOFP consists of a biocompatible Teflon tube and multimode glass fiber which has diffusing area processed with laser and high refractive index resin. The CDOFP was characterized to investigate the clinical feasibility and other applications of light therapy using diffusing optical fiber. The results presented that the CDOFP may be used in clinic by combining with endoscopic method, such as ERCP or EUS, to treat cancer on pancreas and pancreaticobiliary duct.

Paper Details

Date Published: 28 February 2017
PDF: 6 pages
Proc. SPIE 10058, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII, 1005812 (28 February 2017); doi: 10.1117/12.2249025
Show Author Affiliations
Sangyeob Lee, Yonsei Univ. (Korea, Republic of)
Gaye Park, Taihan Fiberoptics Co., Ltd (Korea, Republic of)
Jihoon Park, Yonsei Univ. (Korea, Republic of)
Sungkon Yu, Yonsei Univ. (Korea, Republic of)
Myungjin Ha, Yonsei Univ. (Korea, Republic of)
Seulki Jang, Yonsei Univ. (Korea, Republic of)
Chihwan Ouh, Taihan Fiberoptics Co., Ltd. (Korea, Republic of)
Changhyun Jung, Taihan Fiberoptics Co., Ltd. (Korea, Republic of)
Byungjo Jung, Yonsei Univ. (Korea, Republic of)

Published in SPIE Proceedings Vol. 10058:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
Israel Gannot, Editor(s)

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