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9 October 2021 In vitro study of YLG-1 mediated photodynamic effect on human cancer cells
Na Meng, Xin Wang, Jie Jiang, Rui Ding, Zhen Han, Zheng Huang
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Proceedings Volume 11900, Optics in Health Care and Biomedical Optics XI; 119001R (2021) https://doi.org/10.1117/12.2600758
Event: SPIE/COS Photonics Asia, 2021, Nantong, JS, China
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Abstract
Photosensitizer is a key element of photodynamic therapy (PDT). Currently, only limited numbers of photosensitizers are available for antitumor PDT in China. YLG-1 (Ang-Da-Fen-Qi) is a newly developed second-generation chlorin-type photosensitizer. In this preliminary study, the killing effect of combination of YLG-1 and 652 nm diode laser on human nasopharyngeal carcinoma cells and human ovarian cancer cells were investigated. In vitrostudy suggests that YLG-1 mediated PDT activity has strong cancer cell killing effect and therefore potentials for antitumor PDT applications.
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Na Meng, Xin Wang, Jie Jiang, Rui Ding, Zhen Han, and Zheng Huang "In vitro study of YLG-1 mediated photodynamic effect on human cancer cells", Proc. SPIE 11900, Optics in Health Care and Biomedical Optics XI, 119001R (9 October 2021); https://doi.org/10.1117/12.2600758
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KEYWORDS
Photodynamic therapy
Cancer
In vitro testing
Ovarian cancer
Semiconductor lasers
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