Dr. Giorgio Mattei

Marie Sklodowska-Curie Research Fellow at Optics11 B.V.
Mattei, Giorgio
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Area of Expertise: Tissue Engineering, Biomaterials, Viscoelasticity, Mechanotransduction, Bioreactors
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Profile Summary

Giorgio Mattei was born in Poggibonsi (Siena) in 1986. He received the Bachelor and Master degree (both cum laude) in Biomedical Engineering at the University of Pisa (Italy) in 2008 and 2010, respectively. He obtained a PhD in Chemical and Materials Engineering at the same University in May 2014. Then, he was a Post-Doc researcher at the Research Centre ''E. Piaggio'' (University of Pisa) until October 2016. He won a Horizon 2020 Marie Sklodowska-Curie Individual Fellowship (MSCA-IF) European research grant thanks to which he is currently a Research Fellow at Optics11 B.V. (Amsterdam), VU Amsterdam and LUMC (Leiden) since November 2016.

His research is mainly focused on engineering 3D pathophysiological organ models in-vitro and involves both i) biomaterial design and characterization to develop hydrogel-based smart modular scaffolds for in-vitro cell cultures and ii) computational fluid dynamics (CFD) modelling, design and realization of bioreactors for the dynamic cultivation and real-time monitoring of cell constructs.
His MSCA-IF project (acronym ENDYVE, grant no. 705296) is aimed at engineering the temporal variation of viscoelastic properties of biological tissues (namely, dynamic viscoelasticity) typical of pathophysiological processes in-vivo to investigate its role on cell behavior (focusing on cardiomyocyte maturation).

He filed 2 patents (EP3044306 and EP3115449, granted in Italy), co-authored ~20 publications in high impact international peer-reviewed journals for many of which he serves also as a reviewer (including, among others, Nature Scientific Reports and Acta Biomaterialia).

In addition, he is strongly interested in technology transfer and has co-founded a spin-off company in January 2014 (IVTech s.r.l., www.ivtech.it) devoted to the design of in-vitro technologies for advanced in-vitro cell cultures. He is a member of the IVTech’s board of directors and R&D manager for the development of optically transparent cell culture devices.

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