Photonics West 2022 in San Francisco
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Conference 11960 > Paper 11960-9
Paper 11960-9

Virtual hematoxylin and eosin histopathology with ultraviolet photoacoustic remote sensing and synthetic aperture optical coherence microscopy

Abstract

A combined synthetic aperture optical coherence microscopy and ultraviolet photoacoustic remote sensing system is presented, capable of fast scanning of tissues for tumor margin inspection. It provides a fast 3D OCT mode for imaging tissues to depths of ~1mm, and a superficial virtual histology mode provided by absorption contrast UV-PARS for virtual hematoxylin contrast and coherence-gated scattering microscopy for virtual eosin contrast. Breast lumpectomy specimens are scanned in each mode to evaluate the extent of features in depth and generate en-face images with histological detail and realism, providing results accurately interpretable by pathologists.

Presenter

Univ. of Alberta (Canada)
Presenter/Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)