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Conference 11960 > Paper 11960-104
Paper 11960-104

Resolution and contrast improvement of photoacoustic tomography with two-dimensional frequency domain delay multiply and sum signal reconstruction method


Photoacoustic tomography (PAT) provides bio-imaging with high optical absorption contrast, high acoustic resolution, and deep penetration. Previously, we proposed a frequency domain delay-multiply-and-sum (F-DMAS) signal reconstruction method to axial resolution of optical resolution photoacoustic microscopy. Here we extend the F-DMAS to 2D F-DMAS (2D F-DMAS) and apply 2D F-DMAS to PAT images to improve spatial resolution and contrast simultaneously. Simulations of PAT are used to verify the efficacy of the proposed 2D F-DMAS. The improvement achieved with the proposed method will be further verified by phantom experiments and in vivo imaging.


National Tsing Hua Univ. (Taiwan)
National Tsing Hua Univ. (Taiwan)
National Tsing Hua Univ. (Taiwan)