Photonics West 2022 in San Francisco
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Conference 11960 > Paper 11960-99
Paper 11960-99

High-speed widefield ultraviolet photoacoustic remote sensing via voice-coil stage scanning and an on-demand high pulse-rate pulsed laser

Abstract

An estimated 20-40% of patients who undergo breast-conserving surgery require repeat operations due to the length of time required post-surgery to analyze the resected sample. Recently, a novel non-contact microscopy technique known as ultraviolet photoacoustic remote sensing (UV-PARS) has been developed, which can produce virtual hematoxylin and eosin (H&E) stained images. By using a voice-coil scanning stage in conjunction with an on-demand pulsed laser, we demonstrate 1cm x 1cm gross UV-PARS virtual H&E scans in approximately 50 seconds, along with full-resolution 1cm x 1cm scans in approximately 8 minutes. With widefield high-speed scanning, UV-PARS shows promise for future translation to clinical application.

Presenter

Univ. of Alberta (Canada)
Presenter/Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)
Author
Univ. of Alberta (Canada)