Detection of COVID-19 with bio-sensing fiber comb
One interesting feature of optical frequency comb (OFC) is a function of frequency conversion between region and electric regions. While such feature has been used for generation of correct electric signal in microwave or millimeter region, it can be further used for fiber sensing; namely, sensing OFC. In this paper, we demonstrated detection of SARS-CoV-2 antigen based on a combination of a fiber comb, an intracavity multi-mode-interference fiber sensor, and surface modification of sensor surface with SARS-CoV-2 antibody.
Tokushima Univ. (Japan)