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Conference 11960 > Paper 11960-169
Paper 11960-169

Design and optimiztion of simulated light delivery systems for photoacoustic assessments of peripheral nerve injury

24 January 2022 • 5:30 PM - 7:00 PM PST | Moscone West, Lobby (Level 3)

Abstract

Precise assessment of nerve injury optimizes outcomes after surgical nerve repair. Photoacoustic imaging is a promising technique for this intraoperative assessment, but is challenged by optical scattering which reduces light penetration into nerve tissue. This work investigates custom light delivery methods to enhance optical penetration into nerve tissue using Monte Carlo simulations. Light sources were positioned in four configurations surrounding the nerve using sparse activation patterns that were evenly distributed or clustered. Results indicate that a custom light delivery system with combined radial and lateral trajectory illumination maximize optical penetration into nerve tissue for intraoperative photoacoustic assessment of nerve injury.

Presenter

Johns Hopkins Univ. (United States)
Michelle T. Graham is a final year PhD student in the Department of Electrical and Computer Engineering at Johns Hopkins University. She received her BS degree in biophysics (engineering minor) from the University of Scranton in 2015 and her MSE degree in electrical and computer engineering from Johns Hopkins University in 2018. She is a recipient of the NSF Graduate Research Fellowship, and her research interests include intraoperative photoacoustic imaging, neurosurgical guidance, and translational research.
Presenter/Author
Johns Hopkins Univ. (United States)
Author
The Johns Hopkins Univ. School of Medicine (United States)
Author
The Johns Hopkins Univ. School of Medicine (United States)
Author
Johns Hopkins Univ. (United States)