D-SPR optical fiber plasmonic biosensor for protein detection
This paper demonstrates D-optical fiber plasmonic sensor for sensitive detection of refractive index. The fabrication of D-optical fiber has been performed by wet etching technique for the formation of suitable curvature for the excitation of surface plasmons that resulted in better sensitivity due to the enhanced coupling of surface plasmon polaritons (SPP) modes at the point of discontinuity. Bovine Serum Albumin (BSA) plays an important role in delivering the fatty acid/amino acid etc. In this work, a modified 400micron multimode D shaped fiber coated with a gold thin film of approximately 40-50 nm thickness using Magnetron sputtering unit is used as a sensing platform for the detection of BSA protein. The BSA antibody is immobilized by thiol reduction process over the gold coated sensor surface. The shift in the resonance wavelength in the absorption spectra was studied for RI sensing. The sensitivity of the sensor was calculated to be 1200 nm/RIU.
Central Scientific Instruments Organisation, Council of Scientific & Industrial Research (India)
Priyanka is currently pursuing a Ph.D. from the central Scientific instrumentation organization under the supervision of Dr. Umesh Tiwari, Principal scientist, CSIR-CSIO. she obtained a master's in physical sciences and is currently working on the nanomaterial-functionalized optical fiber sensors for the detection of cancer biomarkers.