Assessing aggressive prostate cancer in intact prostate with a translational needle photoacoustic sensing probe
This study examined the performance of a clinical translatable needle photoacoustic sensing probe in intact prostates removed through prostatectomy procedures. Compared to the prototype probe in our previous studies, the latest version probe possesses fiber optic hydrophone with a dome-shaped tip that provides better sensitivity and sampling volume. The optical components were integrated into a customized clinical standard steel needle with a side opening and protected by medical grade polyurethane. The needle probe was examined in a setup mimicking a transrectal ultrasound guided transperineal prostate biopsy procedure. Preliminary tests showed promising results in differentiating between benign and aggressive cancer tissues in prostate.
Univ. of Michigan Kellogg Eye Ctr. (United States)