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Conference 11954 > Paper 11954-27
Paper 11954-27

A portable time dependent fluorescence lifetime measurement system for rapid assessment of clinically relevant pathogens

Abstract

Pathogens such as bacteria and fungi express various autofluorescence markers such as NAD(P)H, flavins, porphyrins etc. Time dependant fluorescence characteristics of these autofluorescence biomarkers can provide an attractive pathway for detection and classification of pathogens in various clinical settings. Here in, we demonstrate an extremely portable and handheld device powered by Qualcomm based custom designed board for fluorescence lifetime measurement comprising of pulsed LED sources, optical filters, single photon avalanche photodetectors and timing circuits. Fluorescence lifetime characteristics of various pathogens such as Staphylococcus Aureus, Pseudomonas Aeruginosa, E-coli are measured demonstrating the ability of these device to classify pathogens.

Presenter

Bala Pesala
Adiuvo Diagnostics, Ltd. (India)
Bala Pesala is currently a Chief Technology Officer at Adiuvo Diagnostics Private Limited and an adjunct professor at Indian Institute of Technology, Jodhpur, India. His research interests range from Solar energy, Terahertz imaging, Integrated photonics to non-invasive diagnostics. Bala Pesala has received his B.Tech and M.Tech in Aerospace engineering from IIT Madras in 2003. He received his PhD in Electrical Engineering from University of California at Berkeley in 2009. Subsequently, he did his post-doctoral research in the same group on using novel high-contrast gratings for Integrated optics. He received several awards including CSIR Young Scientist Award (2016), Demitri Angelakos memorial achievement award (UC Berkeley 2009), Rafael Rodriguez Golden Age Fellowship (UC Berkeley) and Silver medal for the highest GPA in Aerospace engineering (IIT Madras 2003) to name a few. He has authored/co-authored more than 100 publications in leading peer-reviewed journals and conferences
Author
Adiuvo Diagnostics, Ltd. (India)
Author
Adiuvo Diagnostics, Ltd. (India)
Author
Himakar Reddy
Adiuvo Diagnostics, Ltd. (India)
Author
Adiuvo Diagnostics, Ltd. (India)
Presenter/Author
Bala Pesala
Adiuvo Diagnostics, Ltd. (India)