Optofluidic fiber- based nanoparticle tracking analysis: tool to characterize diffusing nanoscale specimen such as SARS-CoV-2
High-speed tracking of nano-objects is a gateway to understanding biological processes at the nanoscale. Here we will present our results on tracking single or ensembles of nano-objects inside optofluidic fibers via elastic light scattering. The nano-objects diffuse inside a channel of a microstructured fiber and the light scattered by the nano-object is detected transversely via a microscope. We will present the fundamentals of this approach and focus on selected results including retrieval of the full 3D trajectory of a diffusing nano-sphere, the simultaneous detection of hundreds of nano-objects in hollow core anti-resonant fibers and first results on inactivated SARS-CoV-2.
Leibniz-Institut für Photonische Technologien e.V. (Germany)
Markus A. Schmidt owns a full professorship for Fiber Optics at the Friedrich-Schiller University Jena and is head of the research department Fiber Photonics at the Leibniz Institute for Photonic Technologies (IPHT), leading the working group Hybrid Fibers. From 2006 to 2012 he was team leader of the group Nanowire in the division of Philip St. Russell at the Max Planck Institute for the Science of Light in Erlangen. He spent a twelve months research stay in the group of Stefan Maier at the Centre of Plasmonics and Metamaterials at Imperial College London in 2011. He obtained his PhD in 2006 from the Hamburg University of Technology. His main research topic is combining fibers and photonics with applications in areas such as biophotonics, optofluidics, plasmonics and nonlinear optics.
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