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Igor Meglinski

Dr. Igor  Meglinski

Director of Opto-Electronics and Measurement Techniques
University of Oulu

P.O Box 4500

Oulu  90014

tel: 358 29 4488888
fax: 358 8 553 2774
E-mail: igor.meglinski@oulu.fi
Web: http://www.biophotonics.fi

Area of Expertise

Biophotonics, Coherent effects of multiple scattering; Diffusing Wave Spectroscopy, Coherent backscattering, Circularly polarized light for cancer diagnostics, Tissues Optical Clearing, Skin optics, In vivo measurement of skin blood microcirculation. Photon migration & Monte Carlo modelling; Light-tissue interaction.


Dr Igor Meglinski received BSc and MSc in Laser Physics from Saratov State University (Russia), and obtained PhD in Biophysics/Biomedical Optics (1997) at the interface between the University of Pennsylvania (USA) and Saratov State under the supervision of Britton Chance and Professor Valery Tuchin, respectively. Since 2001 he is Head of Bio-Photonics & Bio-Medical Optical Diagnostics in School of Engineering and in Cranfield Health at Cranfield University (UK). Since 2009 he is also Head of Bio-Photonics & Bio-Medical Imaging in the Department of Physics at the University of Otago (New Zealand). Dr. Meglinski's research interests lie at the interface between physics, medicine and biological sciences, focusing on the development of new non-invasive imaging/diagnostic techniques and their application in medicine & biology, material sciences, pharmacy, food, environmental monitoring, and health care industries. He is the Node Leader in Biophotonics4Life Worldwide Consortium (BP4L), and author and co-author over 170 research papers in peer-reviewed scientific journals, proceedings of international conferences and book chapters, and over 230 presentations at major international conferences and workshops, including over 100 invited lectures and plenary talks.

Lecture Title(s)

Optical diagnostics and imaging of blood and lymph vessels and micro-circulation therein: Coherence is a fundamental property of light that has been attracting great attention in the past and an extensive use of lasers in various applications, such as NASA and the European Space Agency's space work, through to modern biology and medicine. By examining the loss of coherence of light due to its dynamic scattering in biological tissues, we observe blood flow and blood micro-circulation in brain and other biological tissues non-invasively in vivo. The particular attention in this lecture is focused on the imaging of blood and lymph vessels and microcirculation therein.

The Poincaré sphere for cancer diagnostics: In this lecture a recent success in application of coherent circularly polarized light for cancer diagnostics and tissues biopsy will be given. It will be demonstrated that circularly and/or elliptical polarized light scattered within the tissues is highly sensitive to the presence of cancer cells and their aggressiveness in tissues. We also show that navigation by Poincaré sphere (similar to the terrestrial globe, using longitude and latitude as in a GPS navigator) is a convenient graphical tool to monitor and determine properties and the condition of biological tissues.

Online computational tool for the needs of Biophotonics and Biomedical Optics: Conceptual engineering design and optimization of laser-based imaging techniques and optical diagnostic systems used in the field of biomedical optics requires a clear understanding of the light-tissue interaction and peculiarities of localization of the detected optical radiation within the medium. The description of photon migration within the turbid tissue-like media is based on the concept of radiative transfer that forms a basis of Monte Carlo (MC) modelling. An opportunity of direct simulation of influence of structural variations of biological tissues on the probing light makes Monte Carlo a primary tool for biomedical optics and optical engineering. Due to the diversity of optical modalities utilizing different properties of light and mechanisms of light-tissue interactions a new Monte Carlo code is typically required to be developed for the particular diagnostic application. In current Lecture introducing an object oriented concept of Monte Carlo modelling and utilizing modern web applications we present the generalized and unified computational tool suitable for the major applications in Biophotonics and Biomedical Optics.


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