Quantification of coronary calcification using high-resolution photon-counting-detector CT and an image domain denoising algorithm
23 February 2022 • 9:00 AM - 9:20 AM PST | Town & Country A
Coronary artery calcification is an important indicator of coronary disease. Accurate volume quantification of coronary calcification using computed tomography (CT) is challenging due to calcium blooming. In this study, ex-vivo coronary specimens were scanned on an investigational photon-counting detector (PCD) CT scanner and the estimated coronary calcification volume were compared with a conventional energy-integrating detector (EID) CT. An image-based denoising algorithm was applied to the PCD-CT images to achieve similar noise levels as EID-CT. Calcifications were segmented to estimate the volume, with micro-CT images of the same calcifications serving as reference. PCD-CT images showed reduced calcium blooming artifacts.
Mayo Clinic (United States)
Dr. VanMeter is a postdoctoral research fellow at the Mayo Clinic CT Clinical Innovation Center. Prior to this, he earned his PhD in physics from the University of Wisconsin-Madison.