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Proceedings Paper

Fast reconstruction of Raman spectra from narrow-band measurements based on Wiener estimation
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Paper Abstract

Raman spectroscopy has demonstrated great potential in the study of biological molecules in a variety of biomedical applications. But slow data acquisition due to weak Raman signals from these molecules has prevented its wide use especially in an imaging setup. We propose a novel method to reconstruct the entire Raman spectrum from a few narrow-band measurements based on Wiener estimation. This method has been tested on Raman spectra from individual cells and shown fast speed and excellent accuracy. This method represents a new direction to speed up Raman data acquisition in an imaging setup to investigate fast changing phenomena.

Paper Details

Date Published: 11 December 2012
PDF: 6 pages
Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85531R (11 December 2012); doi: 10.1117/12.999473
Show Author Affiliations
Shuo Chen, Nanyang Technological Univ. (Singapore)
Yi Hong Ong, Nanyang Technological Univ. (Singapore)
Quan Liu, Nanyang Technological Univ. (Singapore)

Published in SPIE Proceedings Vol. 8553:
Optics in Health Care and Biomedical Optics V
Qingming Luo; Ying Gu; Xingde D. Li, Editor(s)

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