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Proceedings Paper

Wavelength And Dosimetry Considerations In Photoradiation Therapy (PRT)
Author(s): Daniel R. Doiron; Lars O. Svaasand; A. Edward Profio
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Paper Abstract

The effectiveness of hematoporphyrin derivative (HpD) photoradiation therapy (PRT) will depend on (a) the tumor selectivity of HpD, (b) HpD dosage and the delay time between injection and treatment, (c) spectrum of light source, (d) delivered light dose and (e) the optical characteristics of the tissue. Evaluation of the potential useful wavelength of light for HpD-PRT and thier penetration in different tissues have been evaluated. On a theoretical basis, green light (500-520nm) and violet light (400-420nm) will be useful for treating only superficial lesions less than 0.5mm thick while red light (620-640nm) is the light of choice for treatment at depths greater than 0.5mmfor a cat brain tissue.

Paper Details

Date Published: 28 December 1982
PDF: 5 pages
Proc. SPIE 0357, Lasers in Medicine and Surgery, (28 December 1982); doi: 10.1117/12.976072
Show Author Affiliations
Daniel R. Doiron, Childrens Hospital of Los Angeles (United States)
Lars O. Svaasand, University of Trondheim (Norway)
A. Edward Profio, University of California Santa Barbara (United States)

Published in SPIE Proceedings Vol. 0357:
Lasers in Medicine and Surgery
Leon Goldman M.D., Editor(s)

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