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Proceedings Paper

Novel Phenothiazinium Photosensitizers For Photodynamic Therapy
Author(s): Louis Cincotta; James W. Foley; Anthony H. Cincotta
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Paper Abstract

The replament of the oxygen atom in benzophenoxazines with sulfur leads to the corresponding phenothiazinium ehromophorus The effect that this change, as well as other structural alterations, has on photosensitized singlet oxygen formation partitioning coefficient, and in-vitro phototoxicity is presented. A brief discussion concerning how structural modifications can bring about changes in these parameters is also presented. Preliminary results suggest that some phenothiazines could be promising photosensitizers for photodynamic therapy.

Paper Details

Date Published: 17 March 1989
PDF: 9 pages
Proc. SPIE 0997, Advances in Photochemotherapy, (17 March 1989); doi: 10.1117/12.960198
Show Author Affiliations
Louis Cincotta, The Rowland Institute for Science (United States)
James W. Foley, The Rowland Institute for Science (United States)
Anthony H. Cincotta, Louisiana State University (United States)

Published in SPIE Proceedings Vol. 0997:
Advances in Photochemotherapy
Tayyaba Hasan, Editor(s)

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