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Proceedings Paper

A Preliminary Study For An Empirical Approach To An Optical Transform Method For Differentiation Of Pathologies Found In Human Blood Cell Smears
Author(s): James H. K. Yoo
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Paper Abstract

A pilot study for potential applicability of a coherent optical. Fourier transform technique to differentiate between healthy and pathological human blood cell smears has been conducted. Types of abnormalities tested include acute myelogenous leukemia, sickle-cell anemia, target-cell anemia, acute lymphatic leukemia, infectious mononucleosis,and eosincphila. Although limited numbers of slides and restricted types of abnormalities were examined, normality and various abnormalities are distinctly identifiable through coherent optical transform analysis. The morphological and constitutional variations have been qualitatively examined as the sources of both the observed deviations in the characteristic transform patterns and the photographic or densitometric profiles. Limitations in the presently employed optical Fourier transform method and the prerequisite conditions for standardized sample preparation are briefly discussed.

Paper Details

Date Published: 27 December 1977
PDF: 9 pages
Proc. SPIE 0127, Application of Optical Instrumentation in Medicine VI, (27 December 1977); doi: 10.1117/12.955937
Show Author Affiliations
James H. K. Yoo, The University of Texas Health Science Center at San Antonio (United States)

Published in SPIE Proceedings Vol. 0127:
Application of Optical Instrumentation in Medicine VI
Joel E. Gray; William R. Hendee, Editor(s)

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