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Proceedings Paper

Laser Angioplasty With Excimer Laser :Animal Experiment
Author(s): Yuusuke Abe; Tsuneo Chinzei; Kaoru Imanishi; Takumi Yonezawa; Shinichiro Niwa; Koro Yotsuya; Ichiro Sogawa; Takafumi Uemiya; Shinichi Kanazawa; Iwao Fujimasa; Kou Imachi; Masayuki Suzukawa; Kunihiko Mabuchi; Masahiro Asano; Yutaro Tago; Akimasa Kouno; Toshiya Ono; Kazuhiko Atsumi
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Paper Abstract

Excimer laser is able to destruct tissue with less thermal effect. This characteristics was considered to prevent thermal perforation in laser angioplasty. In order to realize coronary laser angioplasty with excimer laser under the visual condition, the basic studies were performed to evaluate the tissue reactions of excimer laser on atheroma and to develop laser endoscopic system for the coronary arteries. The tissue reactions of excimer laser in atheroma were evaluated with rabbit's atherosclerotic aorta, which was made with 1.5% high cholesterol diet. The bigger tissue destruction was obtained in accordance with the increase of the oscillating frequency. Excimer laser indused rather selective destruction of atheroma with high oscillating frequency. The fiber transmission of excimer laser was tried and atheroma was destructed through 400 μm core diameter fiber. Atheroma was observed as like as small lump under endoscopic obsevation, and excimer laser could be irradiated through the fiber under endoscopic view. In order to realize endoscopic application of excimer laser to the coronary arteries, the endoscope was designed from the point of percutaneous approach method to the coronary arteries, and 1.5 mm diameter of endoscope with the channel for laser fiber was developed experimentally. The endoscope could be inserted deeply into the coronary arteries of goat, and the laser irradiation could be performed under endoscopic observation. The possibility of visual coronary laser angioplasty with the combination of excimer laser and coronary endoscope was demonstrated with the endoscope.

Paper Details

Date Published: 11 September 1989
PDF: 8 pages
Proc. SPIE 1066, Laser Surgery: Advanced Characterization, Therapeutics, and Systems, (11 September 1989); doi: 10.1117/12.952037
Show Author Affiliations
Yuusuke Abe, University of Tokyo (Japan)
Tsuneo Chinzei, University of Tokyo (Japan)
Kaoru Imanishi, University of Tokyo (Japan)
Takumi Yonezawa, University of Tokyo (Japan)
Shinichiro Niwa, Sumitomo Electr. Ind., LTD (Japan)
Koro Yotsuya, Sumitomo Electr. Ind., LTD (Japan)
Ichiro Sogawa, Sumitomo Electr. Ind., LTD (Japan)
Takafumi Uemiya, Sumitomo Electr. Ind., LTD (Japan)
Shinichi Kanazawa, Sumitomo Electr. Ind., LTD (Japan)
Iwao Fujimasa, University of Tokyo (Japan)
Kou Imachi, University of Tokyo (Japan)
Masayuki Suzukawa, University of Tokyo (Japan)
Kunihiko Mabuchi, University of Tokyo (Japan)
Masahiro Asano, University of Tokyo (Japan)
Yutaro Tago, University of Tokyo (Japan)
Akimasa Kouno, University of Tokyo (Japan)
Toshiya Ono, University of Tokyo (Japan)
Kazuhiko Atsumi, University of Tokyo (Japan)

Published in SPIE Proceedings Vol. 1066:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems
Kazuhiko Atsumi M.D.; Norman R. Goldblatt; Stephen N. Joffe M.D., Editor(s)

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