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Proceedings Paper

Coloring brain tumor with multi-potent micellar nanoscale drug delivery system
Author(s): Kyuha Chong M.D.; Kyungsun Choi; EunSoo Kim; Eun Chun Han; Jungsul Lee; Junghwa Cha; Taeyun Ku; Jonghee Yoon; Ji Ho Park; Chulhee Choi
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Paper Abstract

Brain tumor, especially glioblastoma multiforme (GBM), is one of the most malignant tumors, which not only demands perplexing treatment approaches but also requires potent and effective treatment modality to deal with recurrence of the tumor. Photodynamic therapy (PDT) is a treatment which has been recommended as a third-level treatment. We are trying to investigate possibility of the PDT as an efficient adjuvant therapeutic modality for the treatment of brain tumor. Inhibition of tumor progression with photosensitizer was verified, in vitro. With micellar nanoscale drug delivery system, localization of the tumor was identified, in vivo, which is able to be referred as photodynamic diagnosis. With consequent results, we are suggesting photodynamic diagnosis and therapy is able to be performed simultaneously with our nanoscale drug delivery system.

Paper Details

Date Published: 24 October 2012
PDF: 6 pages
Proc. SPIE 8548, Nanosystems in Engineering and Medicine, 85480I (24 October 2012); doi: 10.1117/12.946103
Show Author Affiliations
Kyuha Chong M.D., KAIST (Korea, Republic of)
Kyungsun Choi, KAIST (Korea, Republic of)
EunSoo Kim, KAIST (Korea, Republic of)
Eun Chun Han, KAIST (Korea, Republic of)
Jungsul Lee, KAIST (Korea, Republic of)
Junghwa Cha, KAIST (Korea, Republic of)
Taeyun Ku, KAIST (Korea, Republic of)
Jonghee Yoon, KAIST (Korea, Republic of)
Ji Ho Park, KAIST (Korea, Republic of)
Chulhee Choi, KAIST (Korea, Republic of)

Published in SPIE Proceedings Vol. 8548:
Nanosystems in Engineering and Medicine
Sang H. Choi; Jin-Ho Choy; Uhn Lee M.D.; Vijay K. Varadan, Editor(s)

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