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Proceedings Paper

Mapping Bronchial Carcinoma In Situ Lung Cancer Lesions By Combined Imaging Fluorescence Bronchoscopy And Ratioing Fluorometer Probe
Author(s): Oscar J Balchum; A.Edward Profio; Nickolas J Razum
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Paper Abstract

A two-component system of instrumentation and methods, IFB and RFP, when used in combination employing hematoporphyrin derivates, DHE, had highly satisfactory sensitivity (95%) and specificity (100%) for localizing carcinoma in situ lesions in the bronchi of individuals with early stage lung cancer, having a normal chest x-ray and detected by a positive sputum cytology test. The more detailed mapping of additional subjects may increase the specificity of RFP (Ratioing Fluorometer Probe) by itself to an adequate level. Digital computer subs traction of background antofluorescence may increase contrast to enhance the specificity of IFB (Imaging Fluorescence Bronchoscopy).

Paper Details

Date Published: 3 June 1988
PDF: 4 pages
Proc. SPIE 0908, Laser Interaction with Tissue, (3 June 1988); doi: 10.1117/12.945351
Show Author Affiliations
Oscar J Balchum, University of California (United States)
A.Edward Profio, University of California (United States)
Nickolas J Razum, University of California (United States)

Published in SPIE Proceedings Vol. 0908:
Laser Interaction with Tissue
Michael W. Berns, Editor(s)

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