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Proceedings Paper

Pulsed Laser Ablation Of Calcified Plaque
Author(s): M. R. Prince; R. R. Anderson; T. F. Deutsch; G. M. LaMuraglia
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Paper Abstract

Laser ablation of calcific plaque in human arteries has been demonstrated with visible radiation at intensities (107 W/cm2) that are readily transmitted by flexible (320 μm diameter) quartz optical fibers. The ablative mechanism involves formation of a plasma with mechanical fragmentation of the plaque by stress waves rather than simply thermal vaporization. By appropriate selection of laser pulse duration (<50 μsec), wavelength and exposure, the laser pulse can ablate the calcified plaque but will not ablate normal artery. These optimized laser parameters may enhance the safety and efficacy of laser endarterectomy.

Paper Details

Date Published: 21 June 1988
PDF: 5 pages
Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); doi: 10.1117/12.945296
Show Author Affiliations
M. R. Prince, Harvard Medical School (United States)
R. R. Anderson, Harvard Medical School (United States)
T. F. Deutsch, Harvard Medical School (United States)
G. M. LaMuraglia, Harvard Medical School (United States)

Published in SPIE Proceedings Vol. 0906:
Optical Fibers in Medicine III
Abraham Katzir, Editor(s)

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