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Proceedings Paper

Fiber Optic Biosensing Probes For Biomedically Important Compounds
Author(s): Mark A. Arnold
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Paper Abstract

Fiber optic biosensing probes for several bioanalytes of clinical and biomedical importance are described. The development of biosensors based on immobilization of a deaminating enzyme at the tip of a fiber optic ammonia sensor is illustrated with a biosensing probe for urea. In addition, biosensors based on the direct fluorometric detection of reduced nicotinamide adenine dinucleotide (NADH) at the tip of an optical fiber device are presented. Probes for lactate and pyruvate illustrate this concept. Finally, preliminary results from an investigation to prepare NADH sensing probes based on immobilized bacterial luciferase are given.

Paper Details

Date Published: 21 June 1988
PDF: 6 pages
Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988);
Show Author Affiliations
Mark A. Arnold, University of Iowa (United States)

Published in SPIE Proceedings Vol. 0906:
Optical Fibers in Medicine III
Abraham Katzir, Editor(s)

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