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Proceedings Paper

Image Restoration And Interactive Processing For Analysis Of High Resolution Banded Chromosomes.
Author(s): Jim Piper
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Paper Abstract

Digitised prometaphase cells are digitally filtered to restore the image quality. The filter used is based on a non-linear noise filter which corrects only highly deviant picture elements, followed by a 4 by 4 convolution approximation to a Laplacian function, which provides enhancement at the maximum spatial frequency at which the microscope transmits an appreciable signal together with substantial suppression of noise of higher frequency. The system continues by finding the chromosome axis using a skeletonisation procedure, straightens this axis and aligns the bent chromosome along it, thus straightening the chromosome. Sets of straLght chromosomes of like class can then be presented side by side with identified landmark bands aligned.

Paper Details

Date Published: 1 November 1982
PDF: 8 pages
Proc. SPIE 0375, Medical Imaging and Image Interpretation, (1 November 1982); doi: 10.1117/12.934590
Show Author Affiliations
Jim Piper, Western General Hospital (Scotland)

Published in SPIE Proceedings Vol. 0375:
Medical Imaging and Image Interpretation
Judith M. S. Prewitt, Editor(s)

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