We report in this paper some new polarimetric investigations made on pathologically modified human tissues, using the ultra-short laser imaging polarimetry. This technique can be applied for a wide variety of objects with polarization inhomogeneous structure. Real biological tissues have an optically inhomogeneous structure, so any changes produced in the optical polarization state of a light beam passing through such samples (or reflected by them) can reveal important information about the respective biological tissue. The influence of the geometrical architectonics of a cancerous liver tissue on the polarization properties of an ultra-short laser beam who passes through such a sample is radical and can be seen both in the transmitted polarized light, as well as in the SHG (second harmonic generation) polarized light. We used a polarization sensitive imaging system, whose basic optical scheme has been previously published, this time a modified version of the experimental set-up being used. The biological tissue investigated in this paper was a slide of liver tumor. The polarization sensitive intensities for the transmitted and SHG light were measured with two detectors for different polarimetric configurations of the set-up. Experiments show a significant difference between transmitted and, respectively, SHG light behavior.

Date Published: 22 November 2011
PDF: 6 pages
Proc. SPIE 8338, Tenth International Conference on Correlation Optics, 83380B (22 November 2011); doi: 10.1117/12.916609

Published in SPIE Proceedings Vol. 8338:
Tenth International Conference on Correlation Optics
Oleg V. Angelsky, Editor(s)