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Proceedings Paper

Titanium dioxide-cellulose hybrid nanocomposite based conductometric glucose biosensor
Author(s): Mohammad Maniruzzaman; Suresha K. Mahadeva; Abu Hasan Khondoker; Jaehwan Kim
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Paper Abstract

This paper investigates the feasibility of conductometric glucose biosensor based on glucose oxidase (GOx) immobilized TiO2-cellulose hybrid nanocomposite. TiO2 nanoparticles were blended with cellulose solution prepared by dissolving cotton pulp with lithium chloride/N, N-dimethylacetamide solvent to fabricate TiO2-cellulose hybrid nanocomposite. The enzyme (GOx) was immobilized into this hybrid material by physical adsorption method. The successful immobilization of GOx into TiO2-cellulose hybrid nanocomposite via covalent bonding between TiO2 and GOx was confirmed by X-ray photoelectron analysis. The linear response of our propose glucose biosensor is obtained in the range of 1-10mM with correlation coefficient of 0.93. Our study demonstrates TiO2-cellulose hybrid material as a potential candidate for an inexpensive, flexible and disposable glucose biosensor.

Paper Details

Date Published: 30 March 2012
PDF: 5 pages
Proc. SPIE 8344, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012, 83440J (30 March 2012); doi: 10.1117/12.915759
Show Author Affiliations
Mohammad Maniruzzaman, Inha Univ. (Korea, Republic of)
Suresha K. Mahadeva, Inha Univ. (Korea, Republic of)
Abu Hasan Khondoker, Inha Univ. (Korea, Republic of)
Jaehwan Kim, Inha Univ. (Korea, Republic of)

Published in SPIE Proceedings Vol. 8344:
Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012
Vijay K. Varadan, Editor(s)

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