A novel disk-like surface-enhanced Raman scattering (SERS) substrate for bacteria fingerprint discrimination is described. A simple synthesis method for dispersion gold nanoparticles (Au NPs) in the mesoporous silicas matrix with tuneable size and concentrations are also reported. Prepared Au NP-embedded complex matrix was thermal treated at 600 °C for cleaning protecting agent and impurity chemicals to obtain the bare gold NPs (~40 nm) embedded matrix. These prepared matrix present high surface area (≈ 300 m2g-1), large pore size (> 5.0 nm) and high metal NPs content (≈ 30 wt.%). Moreover, a filter-like substrate contains higher water permeability which targets can be filter out from sample solution and the substrates can also perform highly SERS signal compared with normal Raman spectra. Specially, SERS signals can be further adjusted by controlling the size of NPs.

Date Published: 30 January 2012
PDF: 5 pages
Proc. SPIE 8351, Third Asia Pacific Optical Sensors Conference, 83512V (30 January 2012); doi: 10.1117/12.912521

Published in SPIE Proceedings Vol. 8351:
Third Asia Pacific Optical Sensors Conference
John Canning; Gangding Peng, Editor(s)