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Proceedings Paper

Application of anisotropic structure measures for the classification of micro-CT images of human trabecular bone
Author(s): Roberto A. Monetti; Jan Bauer; Irina Sidorenko; Thomas Baum; Ernst Rummeny; Maiko Matsuura; Felix Eckstein; Eva-Maria Lochmueller; Philippe Zysset; Christoph Räth
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Paper Abstract

We analyze μ-CT tomographic images of human trabecular bone in vitro. We consider a sample consisting of 201 bone specimens harvested from six different skeletal sites with bone fraction in the range BV/TV ε [0.04, 0.075]. Using the local characterization of the bone trabecular network given by isotropic and anisotropic scaling indices, we apply classification algorithms in order to reveal structural similarities in the sample. The classification procedures based on isotropic and anisotropic scaling indices lead to different clustering solutions. This comparison helps revealing interesting site specific structural features connected to the intrinsic anisotropy of the trabecular network.

Paper Details

Date Published: 14 April 2012
PDF: 11 pages
Proc. SPIE 8317, Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging, 831716 (14 April 2012); doi: 10.1117/12.911988
Show Author Affiliations
Roberto A. Monetti, Max-Planck-Institut für extraterrestrische Physik (Germany)
Jan Bauer, Technische Univ. München (Germany)
Irina Sidorenko, Max-Planck-Institut für extraterrestrische Physik (Germany)
Thomas Baum, Technische Univ. München (Germany)
Max-Planck-Institut für extraterrestrische Physik (Germany)
Ernst Rummeny, Technische Univ. München (Germany)
Maiko Matsuura, Ludwig-Maximilians-Univ. München (Germany)
Felix Eckstein, Paracelsus Private Medical Univ. (Austria)
Eva-Maria Lochmueller, Ludwig-Maximilians-Univ. München (Germany)
Philippe Zysset, Institute for Surgical Technology & Biomechanics, Univ. of Bern (Switzerland)
Christoph Räth, Max-Planck-Institut für extraterrestrische Physik (Germany)

Published in SPIE Proceedings Vol. 8317:
Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging
Robert C. Molthen; John B. Weaver, Editor(s)

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