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Proceedings Paper

Motion compensation of ultrasonic perfusion images
Author(s): Sebastian Schäfer; Kim Nylund; Odd H. Gilja; Klaus D. Tönnies
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Paper Abstract

Contrast-enhanced ultrasound (CEUS) is a rapid and inexpensive medical imaging technique to assess tissue perfusion with a high temporal resolution. It is composed of a sequence with ultrasound brightness values and a contrast sequence acquired simultaneously. However, the image acquisition is disturbed by various motion influences. Registration is needed to obtain reliable information of spatial correspondence and to analyze perfusion characteristics over time. We present an approach to register an ultrasonography sequence by using a feature label map. This label map is generated from the b-mode data sequence by a Markov-Random-Field (MRF) based analysis, where each location is assigned to one of the user-defined regions according to its statistical parameters. The MRF reduces the chance that outliers are represented in the label map and provides stable feature labels over the time frames. A registration consisting of rigid and non-rigid transformations is determined consecutively using the generated label map of the respective frames for similarity calculation. For evaluation, the standard deviation within specific regions in intestinal CEUS images has been measured before and after registration resulting in an average decrease of 8.6 %. Additionally, this technique has proven to be more robust against noise influence compared to similarity calculation based on image intensities only. The latter leads only to 7.6 % decrease of the standard deviation.

Paper Details

Date Published: 24 February 2012
PDF: 8 pages
Proc. SPIE 8320, Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy, 83200X (24 February 2012); doi: 10.1117/12.911236
Show Author Affiliations
Sebastian Schäfer, Otto-von-Guericke-Univ. Magdeburg (Germany)
Kim Nylund, Institute of Medicine, Univ. of Bergen (Norway)
Helse Bergen Haukeland Univ. Hospital (Norway)
Odd H. Gilja, Institute of Medicine, Univ. of Bergen (Norway)
Helse Bergen Haukeland Univ. Hospital (Norway)
Klaus D. Tönnies, Otto-von-Guericke-Univ. Magdeburg (Germany)

Published in SPIE Proceedings Vol. 8320:
Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy
Johan G. Bosch; Marvin M. Doyley, Editor(s)

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