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Proceedings Paper

Fiber estimation errors incurred from truncated sampling in q-space diffusion magnetic resonance imaging
Author(s): Bryce Wilkins; Namgyun Lee; Manbir Singh
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Paper Abstract

The effect of truncated sphere sampling commonly used in Diffusion Spectrum Imaging to estimate single fiber orientation errors is simulated using fully-sampled (7x7x7) q-space data (343 samples), truncated sphere sampling (203 samples), and zero-padding (to 21x21x21 samples), in both noise-free and noisy (SNR = 30) scenarios. We show that the error of resolving a single fiber direction depends on the fiber orientation relative to the "corners of q-space", which are not sampled when truncated sampling schemes are used, and that corner-samples help reduce the error in estimating a single fiber orientation (mean error 3.5° versus 3.9° for the noise case and zero-padding used). As truncated sphere sampling requires 40% less acquisition time, its use could justify the small increase in error (0.4°). A simulation of the FiberCup phantom was used to assess the significance of truncated sampling on fiber orientation estimation errors over a continuous space of voxels by examining differences in resulting tractography.

Paper Details

Date Published: 24 February 2012
PDF: 10 pages
Proc. SPIE 8314, Medical Imaging 2012: Image Processing, 83144A (24 February 2012); doi: 10.1117/12.911155
Show Author Affiliations
Bryce Wilkins, The Univ. of Southern California (United States)
Namgyun Lee, The Univ. of Southern California (United States)
Manbir Singh, The Univ. of Southern California (United States)

Published in SPIE Proceedings Vol. 8314:
Medical Imaging 2012: Image Processing
David R. Haynor; Sébastien Ourselin, Editor(s)

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