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Proceedings Paper

Age and gender related differences in aortic blood flow
Author(s): Marie Sand Enevoldsen; Mads Møller Pedersen; Martin Christian Hemmsen; Lars Lönn; Kaj-Åge Henneberg; Jørgen Arendt Jensen
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Paper Abstract

The abdominal aorta (AA) is predisposed to development of abdominal aneurysms (AAA), a focal dilatation with fatal consequences if left untreated. The blood flow patterns is thought to play an important role in the development of AAA. The purpose of this work is to investigate the blood flow patterns within a group of healthy volunteers (six females, eight males) aged 23 to 76 years to identify changes and differences related to age and gender. The healthy volunteers were categorized by gender (male/female) and age (below/above 35 years). Subject-specific flow and geometry data were acquired using the research interface on a Profocus ultrasound scanner (B-K Medical, Herlev, Denmark) and segmentation of 3D magnetic resonance angiography (Magnetom Trio, Siemens Healthcare, Erlangen, Germany). The largest average diameter was among the elderly males (19.7 (± 1.33) mm) and smallest among the young females (12.4 (± 0.605) mm). The highest peak systolic velocity was in the young female group (1.02 (± 0.336) m/s) and lowest in the elderly male group (0.836 (± 0.127) m/s). A geometrical change with age was observed as the AA becomes more bended with age. This also affects the blood flow velocity patterns, which are markedly different from young to elderly. Thus, changes in blood flow patterns in the AA related to age and gender are observed. Further investigations are needed to determine the relation between changes in blood flow patterns and AAA development.

Paper Details

Date Published: 24 February 2012
PDF: 11 pages
Proc. SPIE 8320, Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy, 83200J (24 February 2012); doi: 10.1117/12.910859
Show Author Affiliations
Marie Sand Enevoldsen, Technical Univ. of Denmark (Denmark)
Mads Møller Pedersen, Copenhagen Univ. Hospital Rigshopitalet (Denmark)
Martin Christian Hemmsen, Technical Univ. of Denmark (Denmark)
Lars Lönn, Copenhagen Univ. Hospital Rigshopitalet (Denmark)
Kaj-Åge Henneberg, Technical Univ. of Denmark (Denmark)
Jørgen Arendt Jensen, Technical Univ. of Denmark (Denmark)

Published in SPIE Proceedings Vol. 8320:
Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy
Johan G. Bosch; Marvin M. Doyley, Editor(s)

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