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Proceedings Paper

Plasmonic nanobubbles for cell theranostics
Author(s): Ekaterina Y. Lukianova-Hleb; Shruti Kashinath; Dmitri O. Lapotko
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Paper Abstract

A novel transient nanoprobe was developed whose biomedical functions can be dynamically and selectively tuned inside living cells. This probe is not a nanoparticle, but a transient event, a vapor nanobubble generated with a laser pulse around gold (plasmonic) nanoparticles. This is a phenomenon that we recently discovered and named plasmonic nanobubbles (PNBs). PNBs represent an entirely new class of probes due to their dynamic tunability in situ, including single cells. We show that PNB provides highly sensitive diagnosis and immediate follow-up and guided treatment with true nanoscale precision at the level of single cells.

Paper Details

Date Published: 6 February 2012
PDF: 10 pages
Proc. SPIE 8234, Plasmonics in Biology and Medicine IX, 82341F (6 February 2012); doi: 10.1117/12.910639
Show Author Affiliations
Ekaterina Y. Lukianova-Hleb, Rice Univ. (United States)
Shruti Kashinath, Rice Univ. (United States)
Dmitri O. Lapotko, Rice Univ. (United States)

Published in SPIE Proceedings Vol. 8234:
Plasmonics in Biology and Medicine IX
Tuan Vo-Dinh; Joseph R. Lakowicz, Editor(s)

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