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Proceedings Paper

Feasibility of endovascular optical coherence tomography for high-resolution carotid vessel wall imaging
Author(s): Kyle H. Y. Cheng; Cuiru Sun; Juan P. Cruz; Thomas R. Marotta; Julian Spears; Walter J. Montanera; Peter R. Herman; Aman Thind; Brian Courtney; Beau A. Standish; Victor X. D. Yang
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Paper Abstract

Carotid Artery Stenting (CAS) is a procedure that treats carotid atherosclerosis which should be monitored by in vivo high resolution imaging for the quality of the procedure and potential complications. The purpose of this pilot study is to evaluate the ability of optical coherence tomography to construct high resolution two and three dimensional images of stenting in porcine carotid artery for high accuracy diagnostic purposes. Four Yorkshire pigs were anaesthetized and catheterized. A state-of-the-art optical coherence tomography (OCT) system (Lightlab Imaging, St. Jude Medical Inc.) and an automated injector were used to obtain both healthy and stented porcine carotid artery images. Data obtained were then processed for visualization. The state-of-the-art OCT system was able to capture high resolution images of both healthy and stented carotid arteries. High quality three dimensional images of stented carotid arteries were constructed, clearly depicting stent apposition and thrombus formation over different stents. The results demonstrated that current state-of-the-art OCT system can be used to generate high quality three dimensional images of carotid arterial stents for accurate diagnosis of stent apposition and complications under appropriate imaging conditions.

Paper Details

Date Published: 9 February 2012
PDF: 12 pages
Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82074N (9 February 2012); doi: 10.1117/12.910455
Show Author Affiliations
Kyle H. Y. Cheng, Univ. of Toronto (Canada)
Cuiru Sun, Univ. of Toronto (Canada)
Ryerson Univ. (Canada)
Juan P. Cruz, St. Michael's Hospital (Canada)
Thomas R. Marotta, St. Michael's Hospital (Canada)
Julian Spears, St. Michael's Hospital (Canada)
Walter J. Montanera, St. Michael's Hospital (Canada)
Peter R. Herman, Univ. of Toronto (Canada)
Aman Thind, Colibri Technologies Inc. (Canada)
Brian Courtney, Colibri Technologies Inc. (Canada)
Sunnybrook Health Sciences Ctr. (Canada)
Beau A. Standish, Univ. of Toronto (Canada)
Ryerson Univ. (Canada)
Victor X. D. Yang, Univ. of Toronto (Canada)
Ryerson Univ. (Canada)
St. Michael's Hospital (Canada)

Published in SPIE Proceedings Vol. 8207:
Photonic Therapeutics and Diagnostics VIII
Anita Mahadevan-Jansen; Andreas Mandelis; Kenton W. Gregory M.D.; Nikiforos Kollias; Hyun Wook Kang; Henry Hirschberg M.D.; Melissa J. Suter; Brian Jet-Fei Wong M.D.; Justus F. Ilgner M.D.; Stephen Lam; Bodo E. Knudsen M.D.; Steen Madsen; E. Duco Jansen; Bernard Choi; Guillermo J. Tearney M.D.; Laura Marcu; Haishan Zeng; Matthew Brenner; Krzysztof Izdebski, Editor(s)

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