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Proceedings Paper

Implementation of an LED-based clinical spatial frequency domain imaging system
Author(s): Amaan Mazhar; Seyed A. Sharif; Steve Saggese; Bernard Choi; David J. Cuccia; Anthony J. Durkin
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Paper Abstract

Spatial Frequency Domain Imaging (SFDI) is a non-contact imaging method that uses multiple frequency spatial illumination to generate two dimensional maps of tissue optical properties (absorption and reduced scattering) and chromophore concentrations. We present phantom validation and pilot clinical data of a deployed light-emitting diode (LED) based system. The system employs four LED wavelengths (658 nm, 730 nm, 850 nm, 970 nm) to quantitatively assess tissue health by measurement of common tissue constituents. Phantom validation results and maps of oxyhemoglobin, deoxy-hemoglobin, water content, reduced scattering, and surface topography will be presented for pilot studies assessing burn severity and efficacy of port wine stain treatment.

Paper Details

Date Published: 13 February 2012
PDF: 7 pages
Proc. SPIE 8254, Emerging Digital Micromirror Device Based Systems and Applications IV, 82540A (13 February 2012); doi: 10.1117/12.909813
Show Author Affiliations
Amaan Mazhar, Beckman Laser Institute (United States)
Seyed A. Sharif, Beckman Laser Institute (United States)
Steve Saggese, Modulated Imaging, Inc. (United States)
Bernard Choi, Beckman Laser Institute (United States)
David J. Cuccia, Modulated Imaging, Inc. (United States)
Anthony J. Durkin, Beckman Laser Institute (United States)

Published in SPIE Proceedings Vol. 8254:
Emerging Digital Micromirror Device Based Systems and Applications IV
Michael R. Douglass; Patrick I. Oden, Editor(s)

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