
Proceedings Paper
Multispectral photoacoustic coded excitation using pseudorandom codesFormat | Member Price | Non-Member Price |
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Paper Abstract
Photoacoustic imaging (PAI) combines high ultrasound resolution with optical contrast. Laser-generated ultrasound
is potentially beneficial for cancer detection, blood oxygenation imaging, and molecular imaging. PAI
is generally performed using solid state Nd:YAG lasers in combination with optical parametric oscillators. An
alternative approach uses laser diodes with higher pulse repetition rates but lower power. Thus, improvement
in signal-to-noise ratio (SNR) is a key step towards applying laser diodes in PAI. To receive equivalent image
quality using laser diodes as with Nd:YAG lasers, the lower power must be compensated by averaging, which can
be enhanced through coded excitation. In principle, perfect binary sequences such as orthogonal Golay codes
can be used for this purpose when acquiring data at multiple wavelengths. On the other hand it was shown for
a single wavelength that sidelobes can remain invisible even if imperfect sequences are used. Moreover, SNR can
be further improved by using an imperfect sequence compared to Golay codes. Here, we show that pseudorandom
sequences are a good choice for multispectral photoacoustic coded excitation (MSPACE). Pseudorandom
sequences based upon maximal length shift register sequences (m-sequences) are introduced and analyzed for the
purpose of use in MSPACE. Their gain in SNR exceeds that of orthogonal Golay codes for finite code lengths.
Artefacts are introduced, but may remain invisible depending on SNR and code length.
Paper Details
Date Published: 23 February 2012
PDF: 8 pages
Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82231E (23 February 2012); doi: 10.1117/12.907427
Published in SPIE Proceedings Vol. 8223:
Photons Plus Ultrasound: Imaging and Sensing 2012
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)
PDF: 8 pages
Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82231E (23 February 2012); doi: 10.1117/12.907427
Show Author Affiliations
Martin F. Beckmann, Ruhr-Univ. Bochum (Germany)
Claus-Stefan Friedrich, Ruhr-Univ. Bochum (Germany)
Martin P. Mienkina, Ruhr-Univ. Bochum (Germany)
Claus-Stefan Friedrich, Ruhr-Univ. Bochum (Germany)
Martin P. Mienkina, Ruhr-Univ. Bochum (Germany)
Nils C. Gerhardt, Ruhr-Univ. Bochum (Germany)
Martin R. Hofmann, Ruhr-Univ. Bochum (Germany)
Georg Schmitz, Ruhr-Univ. Bochum (Germany)
Martin R. Hofmann, Ruhr-Univ. Bochum (Germany)
Georg Schmitz, Ruhr-Univ. Bochum (Germany)
Published in SPIE Proceedings Vol. 8223:
Photons Plus Ultrasound: Imaging and Sensing 2012
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)
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