
Proceedings Paper
Confocal microlaparoscope for imaging the fallopian tubeFormat | Member Price | Non-Member Price |
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Paper Abstract
Recent evidence suggests that epithelial ovarian cancer may originate in the fimbriated end of the fallopian tube1. Unlike
many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this
deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. We have previously
reported on a rigid confocal microlaparoscope system that is currently undergoing a clinical trial to image the epithelial
surface of the ovary2. In order to gain in vivo access to the fallopian tubes we have developed a new confocal
microlaparoscope with an articulating distal tip. The new instrument builds upon the technology developed for the
existing confocal microlaparoscope. It has an ergonomic handle fabricated by a rapid prototyping printer. While
maintaining compatibility with a 5 mm trocar, the articulating distal tip of the instrument consists of a 2.2 mm diameter
bare fiber bundle catheter with automated dye delivery for fluorescence imaging. This small and flexible catheter design
should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube. Early
ex vivo mages of human fallopian tube and in vivo imaging results from recent open surgeries using the rigid confocal
microlaparoscope system are presented. Ex vivo images from animal models using the new articulating bare fiber system
are also presented. These high quality images collected by the new flexible system are similar in quality to those
obtained from the epithelial surface of ovaries with the rigid clinical confocal microlaparoscope.
Paper Details
Date Published: 2 March 2012
PDF: 6 pages
Proc. SPIE 8217, Endoscopic Microscopy VII, 82170O (2 March 2012); doi: 10.1117/12.906430
Published in SPIE Proceedings Vol. 8217:
Endoscopic Microscopy VII
Guillermo J. Tearney; Thomas D. Wang M.D., Editor(s)
PDF: 6 pages
Proc. SPIE 8217, Endoscopic Microscopy VII, 82170O (2 March 2012); doi: 10.1117/12.906430
Show Author Affiliations
Tzu-Yu Wu, College of Optical Sciences, Univ. of Arizona (United States)
Univ. of Arizona (United States)
Rachel Schafer, Univ. of Arizona (United States)
Univ. of Arizona (United States)
Rachel Schafer, Univ. of Arizona (United States)
Andrew R. Rouse, Univ. of Arizona (United States)
Arthur F. Gmitro, College of Optical Sciences, Univ. of Arizona (United States)
Univ. of Arizona (United States)
Arthur F. Gmitro, College of Optical Sciences, Univ. of Arizona (United States)
Univ. of Arizona (United States)
Published in SPIE Proceedings Vol. 8217:
Endoscopic Microscopy VII
Guillermo J. Tearney; Thomas D. Wang M.D., Editor(s)
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