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Proceedings Paper

Wavelength multiplexing for FD-OCT speckle averaging
Author(s): Gijs van Soest; Evelyn Regar; Brett E. Bouma; Guillermo J. Tearney; Antonius F. W. van der Steen
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Paper Abstract

Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.

Paper Details

Date Published: 9 February 2012
PDF: 7 pages
Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 820742 (9 February 2012); doi: 10.1117/12.906335
Show Author Affiliations
Gijs van Soest, Erasmus MC (Netherlands)
Evelyn Regar, Erasmus MC (Netherlands)
Brett E. Bouma, Wellman Ctr. for Photomedicine, Massachusetts General Hospital (United States)
Guillermo J. Tearney, Wellman Ctr. for Photomedicine, Massachusetts General Hospital (United States)
Antonius F. W. van der Steen, Erasmus MC (Netherlands)
Interuniversity Cardiology Institute of the Netherlands (Netherlands)

Published in SPIE Proceedings Vol. 8207:
Photonic Therapeutics and Diagnostics VIII
Anita Mahadevan-Jansen; Andreas Mandelis; Kenton W. Gregory M.D.; Nikiforos Kollias; Hyun Wook Kang; Henry Hirschberg M.D.; Melissa J. Suter; Brian Jet-Fei Wong M.D.; Justus F. Ilgner M.D.; Stephen Lam; Bodo E. Knudsen M.D.; Steen Madsen; E. Duco Jansen; Bernard Choi; Guillermo J. Tearney M.D.; Laura Marcu; Haishan Zeng; Matthew Brenner; Krzysztof Izdebski, Editor(s)

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