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Proceedings Paper

Ultrafast time-dependent fluorescence spectroscopy for human breast cancer detection
Author(s): Yang Pu; Guichen Tang; B. B. Das; C.-H. Liu; Asima Pradhan; Robert R. Alfano
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Paper Abstract

Time-resolved fluorescence emission from normal breast tissue, benign and malignant breast tumors were measured using excitation of 100 fs pulses at 310nm. Fluorescence relaxation decay parameters were extracted from the measured temporal emission profiles. The decay times and amplitudes of fast and slow profiles of malignant tissues were different from normal and benign tissues, which allows the malignant tumor to be separated from non-malignant breast tissue. The differences between the decay times of slow and fast component can be explained by tissue structure changes during breast cancer evolution.

Paper Details

Date Published: 31 January 2012
PDF: 5 pages
Proc. SPIE 8220, Optical Biopsy X, 82200X (31 January 2012); doi: 10.1117/12.906254
Show Author Affiliations
Yang Pu, The City College of New York (United States)
Guichen Tang, The City College of New York (United States)
B. B. Das, Fairfield Univ. (United States)
C.-H. Liu, The City College of New York (United States)
Asima Pradhan, Indian Institute of Technology Kanpur (India)
Robert R. Alfano, The City College of New York (United States)

Published in SPIE Proceedings Vol. 8220:
Optical Biopsy X
Robert R. Alfano; Stavros G. Demos, Editor(s)

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