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Proceedings Paper

Dielectrophoresis of micro/nano particles using curved microelectrodes
Author(s): Khashayar Khoshmanesh; Francisco J. Tovar-Lopez; Sara Baratchi; Chen Zhang; Aminuddin A. Kayani; Adam F. Chrimes; Saeid Nahavandi; Donald Wlodkowic; Arnan Mitchell; Kourosh Kalantar-zadeh
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Paper Abstract

Dielectrophoresis, the induced motion of polarisable particles in non-homogenous electric field, has been proven as a versatile mechanism to transport, immobilise, sort and characterise micro/nano scale particle in microfluidic platforms. The performance of dielectrophoretic (DEP) systems depend on two parameters: the configuration of microelectrodes designed to produce the DEP force and the operating strategies devised to employ this force in such processes. This work summarises the unique features of curved microelectrodes for the DEP manipulation of target particles in microfluidic systems. The curved microelectrodes demonstrate exceptional capabilities including (i) creating strong electric fields over a large portion of their structure, (ii) minimising electro-thermal vortices and undesired disturbances at their tips, (iii) covering the entire width of the microchannel influencing all passing particles, and (iv) providing a large trapping area at their entrance region, as evidenced by extensive numerical and experimental analyses. These microelectrodes have been successfully applied for a variety of engineering and biomedical applications including (i) sorting and trapping model polystyrene particles based on their dimensions, (ii) patterning carbon nanotubes to trap low-conductive particles, (iii) sorting live and dead cells based on their dielectric properties, (iv) real-time analysis of drug-induced cell death, and (v) interfacing tumour cells with environmental scanning electron microscopy to study their morphological properties. The DEP systems based on curved microelectrodes have a great potential to be integrated with the future lab-on-achip systems.

Paper Details

Date Published: 23 December 2011
PDF: 9 pages
Proc. SPIE 8204, Smart Nano-Micro Materials and Devices, 82040G (23 December 2011); doi: 10.1117/12.903183
Show Author Affiliations
Khashayar Khoshmanesh, Deakin Univ. (Australia)
Francisco J. Tovar-Lopez, RMIT Univ. (Australia)
Sara Baratchi, Monash Univ. (Australia)
Chen Zhang, Univ. of South Australia (Australia)
Aminuddin A. Kayani, RMIT Univ. (Australia)
Adam F. Chrimes, RMIT Univ. (Australia)
Saeid Nahavandi, Deakin Univ. (Australia)
Donald Wlodkowic, Univ. of Auckland (New Zealand)
Arnan Mitchell, RMIT Univ. (Australia)
Kourosh Kalantar-zadeh, RMIT Univ. (Australia)

Published in SPIE Proceedings Vol. 8204:
Smart Nano-Micro Materials and Devices
Saulius Juodkazis; Min Gu, Editor(s)

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