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Proceedings Paper

Second harmonic nanoparticles in imaging applications
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Paper Abstract

Nanocrystals with second harmonic response is a new class of nonlinear optical nanoprobes with dramatically different properties from fluorescent agents. Compared with two-photon fluorescence, second harmonic generation is an ultrafast, lossless, and coherent process. In particular, the absence of photobleaching and emission intermittency in the optical response of the second harmonic nanoparticles is likely to complement the fluorescent agents widely used today in many imaging applications. Furthermore, the coherent emission from the second harmonic generation process provides unique opportunities for the application of coherence domain techniques that are not available with fluorescent agents. We review the application of the second harmonic nanocrystals in imaging applications, especially those pertaining to biomedicine.

Paper Details

Date Published: 12 September 2011
PDF: 9 pages
Proc. SPIE 8095, Active Photonic Materials IV, 80950E (12 September 2011); doi: 10.1117/12.894567
Show Author Affiliations
Ye Pu, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Chia-Lung Hsieh, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
California Institute of Technology (United States)
Rachel Grange, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Friedrich Schiller Univ. (Germany)
Xin Yang, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Ioannis Papadopoulos, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Jae-Woo Choi, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Demetri Psaltis, Ecole Polytechnique Fédérale de Lausanne (Switzerland)

Published in SPIE Proceedings Vol. 8095:
Active Photonic Materials IV
Ganapathi S. Subramania; Stavroula Foteinopoulou, Editor(s)

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