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Proceedings Paper

Surface enhanced Raman scattering (SERS)-based next generation commercially available substrate: physical characterization and biological application
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Paper Abstract

The development of a sensing platform capable of detecting and identifying hazards including biological, chemical, and energetic in nature is a long sought after goal of the Army and many other first responders. Surface enhanced Raman scatting (SERS) is one spectroscopic technique gaining popularity as a solution to many sensing needs due to its many advantages such as high sensitivity, little to no sample preparation required, and use in numerous environmental settings). Despite all the advantages of SERS, it still remains a marginalized sensing technique primarily due to the challenges in fabricating a reliable, highly sensitive and reproducible nanoscale surface. In this work, we show that many of these challenges have been overcome with a newly developed commercially available Klarite SERS substrate. These substrates are fabricated in a fashion similar to standard Klarite substrates, but due to changes in size and spacing of the inverted pyramidal structurethere is an overall increase of SERS sensing capabilities of up to 4 orders of magnitude. In this proceeding paper, the next generation Klarite (308 and 309) substrates are characterized, analyte sensitivity demonstrated at 633 nm and 785 nm, and a brief discussion of their biological sensing capabilities is presented.

Paper Details

Date Published: 12 September 2011
PDF: 10 pages
Proc. SPIE 8099, Biosensing and Nanomedicine IV, 80990N (12 September 2011); doi: 10.1117/12.893842
Show Author Affiliations
Mikella E. Hankus, U.S. Army Research Lab. (United States)
Dimitra N. Stratis-Cullum, U.S. Army Research Lab. (United States)
Paul M. Pellegrino, U.S. Army Research Lab. (United States)

Published in SPIE Proceedings Vol. 8099:
Biosensing and Nanomedicine IV
Hooman Mohseni; Massoud H. Agahi; Manijeh Razeghi, Editor(s)

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