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Proceedings Paper

Towards single cell spectroscopy and refractometry in microfluidic chip platforms
Author(s): J. B. Tillak; I. Bernacka-Wojcik; D. Barata; P. A. S. Jorge; H. Águas; A. G. Oliva
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Paper Abstract

This paper evaluates various strategies proposed for single cell refractometry and spectroscopy using fiber optic sensors and microfluidic chips. Details concerning design, fabrication and characterization of the chips will be addressed. Preliminary results obtained with alternative on-chip configurations using combination of fiber Bragg gratings with mirrored single mode and multimode fibers will be presented indicating the possibility of performing simultaneous assessment of cellular refractive index and absorption properties.

Paper Details

Date Published: 26 July 2011
PDF: 8 pages
Proc. SPIE 8001, International Conference on Applications of Optics and Photonics, 800112 (26 July 2011); doi: 10.1117/12.892180
Show Author Affiliations
J. B. Tillak, INESC Porto (Portugal)
I. Bernacka-Wojcik, Ciência dos Materiais (Portugal)
D. Barata, Ciência dos Materiais (Portugal)
Biomolecular Diagnostics Lab., ITQB-UNL/IBET (Portugal)
P. A. S. Jorge, INESC Porto (Portugal)
H. Águas, Ciência dos Materiais (Portugal)
A. G. Oliva, Biomolecular Diagnostics Lab., ITQB-UNL/IBET (Portugal)

Published in SPIE Proceedings Vol. 8001:
International Conference on Applications of Optics and Photonics
Manuel Filipe Costa, Editor(s)

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