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Proceedings Paper

Slow spontaneous hemodynamic oscillations during sleep measured with near-infrared spectroscopy
Author(s): Jaakko Virtanen; Tiina Näsi; Tommi Noponen; Jussi Toppila; Tapani Salmi; Risto J. Ilmoniemi
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Paper Abstract

Spontaneous cerebral hemodynamic oscillations below 100 mHz reflect the level of cerebral activity, modulate hemodynamic responses to tasks and stimuli, and may aid in detecting various pathologies of the brain. Near-infrared spectroscopy (NIRS) is ideally suited for both measuring spontaneous hemodynamic oscillations and monitoring sleep, but little research has been performed to combine these two applications. We analyzed 30 all-night NIRS-electroencephalography (EEG) sleep recordings to investigate spontaneous hemodynamic activity relative to sleep stages determined by polysomnography. Signal power of hemodynamic oscillations in the low-frequency (LF, 40-150 mHz) and very-low-frequency (VLF, 3-40 mHz) bands decreased in slow-wave sleep (SWS) compared to light sleep (LS) and rapid-eye-movement (REM) sleep. No statistically significant (p < 0.05) differences in oscillation power between LS and REM were observed. However, the period of VLF oscillations around 8 mHz increased in REM sleep in line with earlier studies with other modalities. These results increase our knowledge of the physiology of sleep, complement EEG data, and demonstrate the applicability of NIRS to studying spontaneous hemodynamic fluctuations during sleep.

Paper Details

Date Published: 9 June 2011
PDF: 9 pages
Proc. SPIE 8088, Diffuse Optical Imaging III, 808806 (9 June 2011); doi: 10.1117/12.889480
Show Author Affiliations
Jaakko Virtanen, Aalto Univ. (Finland)
Helsinki Univ. Central Hospital (Finland)
Tiina Näsi, Aalto Univ. (Finland)
Helsinki Univ. Central Hospital (Finland)
Tommi Noponen, Turku Univ. Hospital (Finland)
Jussi Toppila, Helsinki Univ. Central Hospital (Finland)
Tapani Salmi, Helsinki Univ. Central Hospital (Finland)
Risto J. Ilmoniemi, Aalto Univ. (Finland)
Helsinki Univ. Central Hospital (Finland)

Published in SPIE Proceedings Vol. 8088:
Diffuse Optical Imaging III
Andreas H. Hielscher; Paola Taroni, Editor(s)

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