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Proceedings Paper

Study on image feature extraction and classification for human colorectal cancer using optical coherence tomography
Author(s): Shu-Wei Huang; Shan-Yi Yang; Wei-Cheng Huang; Han-Mo Chiu; Chih-Wei Lu
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Paper Abstract

Most of the colorectal cancer has grown from the adenomatous polyp. Adenomatous lesions have a well-documented relationship to colorectal cancer in previous studies. Thus, to detect the morphological changes between polyp and tumor can allow early diagnosis of colorectal cancer and simultaneous removal of lesions. OCT (Optical coherence tomography) has been several advantages including high resolution and non-invasive cross-sectional image in vivo. In this study, we investigated the relationship between the B-scan OCT image features and histology of malignant human colorectal tissues, also en-face OCT image and the endoscopic image pattern. The in-vitro experiments were performed by a swept-source optical coherence tomography (SS-OCT) system; the swept source has a center wavelength at 1310 nm and 160nm in wavelength scanning range which produced 6 um axial resolution. In the study, the en-face images were reconstructed by integrating the axial values in 3D OCT images. The reconstructed en-face images show the same roundish or gyrus-like pattern with endoscopy images. The pattern of en-face images relate to the stages of colon cancer. Endoscopic OCT technique would provide three-dimensional imaging and rapidly reconstruct en-face images which can increase the speed of colon cancer diagnosis. Our results indicate a great potential for early detection of colorectal adenomas by using the OCT imaging.

Paper Details

Date Published: 1 June 2011
PDF: 4 pages
Proc. SPIE 8091, Optical Coherence Tomography and Coherence Techniques V, 80911Y (1 June 2011); doi: 10.1117/12.888778
Show Author Affiliations
Shu-Wei Huang, Industrial Technology Research Institute (Taiwan)
Shan-Yi Yang, Industrial Technology Research Institute (Taiwan)
Wei-Cheng Huang, Industrial Technology Research Institute (Taiwan)
Han-Mo Chiu, National Taiwan Univ. Hospital (Taiwan)
Chih-Wei Lu, Industrial Technology Research Institute (Taiwan)

Published in SPIE Proceedings Vol. 8091:
Optical Coherence Tomography and Coherence Techniques V
Rainer A. Leitgeb; Brett E. Bouma, Editor(s)

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